Welcome to my homepage
I am an international research scientist, specialized in chromosome biology and molecular oncology.
With an analytical mind and being passionate about innovation and improvement, over the years, I have acquired wide knowledge and experience in a broad variety of techniques in molecular biology and protein biochemistry, strong skills in scientific publication, grant writing, and I have successful mentored undergraduate students and technicians.
Additionally, I have developed valuable transferable skills such as strong time management, notable adaptability, project management and concise communication. I have also developed and conducted projects outside the lab in a collaborative team setting. I enjoy working in data-driven problem-solving environments, and I am an advocate for technology transfer and science outreach.
Current Research Projects
1- Proteomics of the response to Double Strand Breaks
2- Role of Liquid-Liquid Phase separation in DNA repair
3- Functional characterization of DNA repair modules
Selected Journal Publications
Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, Gottesman M, Gautier J Nuclear Arp2/3 drives DNA break clustering for homology-directed repair. Nature (2018) Nature. 2018 Jul;559(7712):61-66. PMID: 29925947
Aparicio T, Peterson S, Gottesman M, Gautier J. MRN, CtIP and BRCA1 mediate repair of Topoisomerase II-DNA adducts. The Journal of Cell Biology (2016) 212(4):399-408. PMID: 26880199. PMID: 27652321
Aparicio T, Baer R. Gautier J. DNA double-strand break repair pathway choice and cancer DNA repair. (2014) 19:169-75. PMID: 24746645